On March 9th, Dr. Laganà published some preliminary data proceeding
the 16th World Congress of Gynecological Endocrinology on ovarian function and metabolic factors in women affected by PCOS after treatment with D-chiro-inositol. (1) The study looked at 25 patients affected by PCOS and menstrual irregularities. The patients underwent treatment with 1 g of D-Chiro-Inositol plus 400 mcg of Folic Acid orally for 6 months. After the 6 months there was a statistically significant reduction of the Systolic blood pressure, Gallwey-Ferriman Score, LH, LH/FSH ratio, total Testosterone, free Testosterone, ∆-4-Androstenedione, Prolactin and HOMA Index; in the same patients there was a statistically significant increase of SHBG and Glycemia/IRI ratio. Moreover, there was a statistically significant (64%; p<0.05) post-treatment menstrual cycle regularization.http://pcosdiva.com/2014/03/positive-pcos-research-inositol/
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